Endocrine Abstracts

Inappropriately low circulating PTH levels following thyroid surgery, is the most common cause of iatrogenic hypocalcaemia. Standard treatment of hypoparathyroidism has comprised vitamin D analogue and calcium supplementation. However some patients remain hypocalcaemic despite use of maximal titrated and tolerated therapy. Teriparatide is recombinant formulation of endogenous PTH, containing 34 amino acid sequence which is identical to the N-terminal portion of this hormone. W...

A 46 year old female presented with 12 months history of secondary amenorrhoea. Prolactin was 4746 mIU/l without macroprolactin complexes, LH & FSH were low, oestradiol was undetectable. She had normal visual fields. No other clinical or biochemical features of pituitary dysfunction. She had no regular medication. Pituitary MRI was normal. She was started on cabergoline 250 mcg twice weekly which was subsequently increased to 500 mcg twice weekly. Repeat serum prolactin 5 ...